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This 2026 study by Feel30 examines the important questions that Americans are asking about testosterone replacement therapy (TRT), exploring topics from the cost of treatment to the side effects that come with it.
When it comes to testosterone replacement therapy, the question that Americans are searching for the most is also the simplest: “What is TRT?”
This query has generated an estimated 264,700 U.S. searches over 12 months.
Other queries include:
Feel30, a telehealth brand that specializes in men’s health and TRT, analyzed search estimates from September 2025 through August 2026 to discover the information people want to know.
To complete the analysis, Feel30 reviewed 361 keyword rows. They excluded identified brand searches, celebrity searches, and unrelated searches, which left them with a retained set of 312 terms. Those terms had a combined estimated U.S. search volume of 3,370,080.
Upon analyzing the retained terms, they found that:
The figures discussed are a measurement of estimated search activity, and are not reflective of patient numbers. See the bottom of the article for the methodology used.
TRT stands for testosterone replacement therapy. This treatment is prescribed for patients diagnosed with a testosterone deficiency (known medically as “male hypogonadism”). According to clinical guidance provided by the Endocrine Society (2018), to be diagnosed, patients need to present the correct symptoms such as, but not limited to, chronic fatigue, mood swings, hair loss, and an increase in body fat, as well as undergo blood testing that will confirm if testosterone levels are low.
Here’s a full breakdown of the top 10 TRT keywords. They cover a wide range of subtopics and highlight the information Americans want to know regarding treatment, safety, access, cost, and hair loss.
Table showing the top 10 ranking search terms related to TRT, and their estimated annual U.S. searches. Search wording is reproduced as recorded.
“What is TRT?” is the biggest search term at Rank 1, attracting more than three times the estimated volume of “side effects of TRT” (Rank 2), at 72,900. “Is TRT safe?” comes in third with 52,500 searches.
The ranking shows a mix of different types of keywords, including direct questions and information-seeking phrases such as “TRT meaning” (Rank 4) and “Is TRT steroids” (Rank 6).
Across 29 terms about price and insurance, the combined estimated annual search volume reached 253,520. The seven included in the table below give an overview of the importance Americans place on the costs of TRT.
Table showing the search terms related to TRT costs and their estimated annual U.S. searches. Search wording is reproduced as recorded.
The biggest term in this group is “TRT cost” at 66,100. The rest of the terms give more insight into how people think, identifying demand for information around cost, with a strong emphasis on whether TRT is covered by insurance. However, it does not show whether people have been refused coverage or found treatment unaffordable.
Feel30’s research examined both hair loss and fertility searches. They tracked seven hair-loss terms, totaling 47,920, compared with 26,490 across five terms about fertility, infertility, sperm count, and pregnancy. The data show that the estimated volume of searches for hair loss keywords was 81% higher than for fertility.
Table showing search terms related to TRT and hair loss and fertility, and their estimated annual U.S. searches. Search wording is reproduced as recorded.
The difference in searches between hair loss and fertility can be seen in the individual leading questions. For example, “Does TRT cause hair loss?” had a search volume of 23,500, as opposed to “does TRT make you infertile?” which had 15,900.
However, does this mean that Americans find the relationship between testosterone and hair loss more important than the one between TRT and fertility? Not necessarily. The comparison only describes the terms people have been searching for, but it cannot tell us which concern matters more to an individual. This doesn’t mean one person cares less about how TRT can affect fertility than they do hair loss.
The following search terms showed that people have concerns around stopping TRT treatment. Feel30 identified 16 search terms that related to:
When combined, the estimated annual volume came to 34,830.
Table showing search terms related to coming off TRT and their estimated annual U.S. searches. Search wording is reproduced as recorded.
From the table above, it’s clear to see that “coming off TRT after 6 months” is the largest keyword, at 6,700.
The search terms indicate that people may be interested in the commitment that TRT treatment involves, as well as how long testosterone stays in your system. This doesn’t necessarily mean that individuals started treatment and decided to come off after six months. Someone researching “coming off TRT” may not have started treatment at all.
As well as the duration of treatment, people who are considering TRT may also have questions surrounding:
The analysis that Feel30 completed around weight loss and muscle searches found that:
Weight-loss searches were 2.6 times higher than muscle searches.
They found:
Feel30 also found that:
Table showing search terms related to face changes and TRT, and their estimated annual U.S. searches. Search wording is reproduced as recorded.
“Before and after” comparison appeared in both groups. They were also prevalent in keywords around facial appearance, including “TRT face before and after,” as highlighted in the table above. Five face-related terms came to a total of 19,330.
These searches indicate that people are interested in the visible changes they might see when undergoing TRT. However, just because people are searching for queries about weight loss, muscle loss, or a change in facial appearance, it is not proof that the treatment delivers those specific results. Individual results can vary from person to person, and detailed guides such as how long TRT takes to work can explain why.
Table showing the estimated annual U.S. searches and searches per 100,000 residents. The table covers all 50 states and all 312 retained terms. Rates use total resident populations, not adult male populations, and are rounded to one decimal place.
* The above rankings from Feel30’s study are based on search-volume rankings only. They are not rankings of testosterone deficiency diagnosis or treatment use.
Feel30 also examined TRT searches by state. They found:
While the dataset shows that California, Texas, and Florida may have the biggest annual searches, when population is taken into account, they rank 41st, 46th, and 40th, respectively. This is an important distinction because the total volume shows where the largest amount of estimated search activity occurs. Once adjusted based on population, this metric means that differently sized states can be compared using the same set of keywords.
Feel30 found that when they looked at individual queries, the overall rankings changed considerably. For example, when it came to the keyword “what is TRT”:
But when it came to “side effects of TRT,” these were the results:
In regard to “TRT meaning,” California recorded 11,040 searches, which was roughly equivalent to one-quarter of the independently estimated U.S. volume of 44,200 for that phrase.
Feel30 found that, in every state they compared, “what is TRT” was the leading information query. The difference between the states lay in the volume of search activity rather than the question itself.
The searches analyzed here show the type of information people are interested in knowing about TRT, and offer a useful starting point for the questions to bring up at a consultation:
However, these search results alone can’t determine whether a person has a testosterone deficiency, which can only be established by assessing symptoms and medical history, as well as reviewing blood test results – all of which need to be carried out by a qualified clinician. Feel30's testosterone replacement therapy page has more information about evaluation and diagnosis, as well as the different TRT treatment types.
In order to conduct this analysis, Feel30 reviewed a supplied dataset of 361 keyword rows. These keywords had been identified from terms containing “TRT” or “testosterone replacement therapy” using Ahrefs Keywords Explorer.
The figures are monthly Google search estimates for September 2025 through August 2026, collected on September 29, 2026.
To conduct a fair analysis, Feel30 excluded 49 rows, which included:
They then recalculated totals from the remaining 312 rows. Their workbook's (raw spreadsheet) original aggregate figures are therefore different from the revised figures reported here.
National figures use the workbook's U.S. estimates. State totals are calculated separately from its state-level estimates; they don’t add up to the national estimate and should not be substituted for it.
State rates were calculated as:
Estimated annual state search volume ÷ state population × 100,000.
Feel30 used the 2025 population estimates supplied in the workbook, which attributes them to the U.S. Census Bureau. The analysis covered the 50 states and excluded Washington, D.C.
Direct questions and information-seeking phrases such as “what is TRT” were present in the source, but hadn’t originally been tagged as a query. Standalone searches such as “TRT” were left out of the ranking, as well as general product and provider-based searches.
When it came to comparing topics, Feel30 grouped the relevant keyword rows and added their U.S. estimates as follows:
Topic groups are made up of different numbers of terms. Their combined estimates shouldn’t be read as counts of separate searches or people searching. Related phrases may overlap: one person may search three phrases in five minutes, or one phrase may cover multiple ideas.
“TRT” is a generic abbreviation and may also have other meanings outside testosterone therapy.
Rankings that have been adjusted by population can also be affected by low-volume estimates, rounding, and keyword selection, especially in smaller states.
The data provided cannot identify the searchers’ age, gender, diagnosis, or treatment status. Nor can it establish the medical reality, including the frequency of side effects, as well as measure historical trends based on previous years.
Note for Editors
The above research was conducted by Feel30, a telehealth brand specializing in TRT and men’s health. Journalists are welcome to use their findings to support their own work, but ensure to credit Feel30 and this research page as the original source so that readers are able to access the data and methodology used.
All figures should be described as “estimated search volumes.” Do not present them as numbers of patients, people diagnosed with low testosterone, or people experiencing side effects.
Use the revised 312-term analysis for the findings in this article, rather than the original workbook's unfiltered totals.
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